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Aberrant replication licensing drives Copy Number Gains across species

Patroula Nathanailidou, Michalis Petropoulos, Styliani Maxouri, et al.

Selected by 12 October 2020

Yasmin Lau

Genetics

Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice

Yuki Nishimoto, Kazuhiro Ito, Genki Kimura, et al.

Selected by 23 September 2020

Zhang-He Goh

Pharmacology and Toxicology

The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection

Silvia Ferrara, Alice Rossi, Serena Ranucci, et al.

Selected by 25 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model

Kristina M. Bigelow, Rokeya Tasneen, Yong S. Chang, et al.

Selected by 01 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Hyperactive end joining repair mediates resistance to DNA damaging therapy in p53-deficient cells

Rashmi J. Kumar, Hui Xiao Chao, Victoria R. Roberts, et al.

Selected by 24 June 2020

Matthew Burke

Cell Biology

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, et al.

Selected by 18 June 2020

Zhang-He Goh

Pharmacology and Toxicology

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

Ruben Schep, Eva Brinkman, Christ Leemans, et al.

Selected by 11 June 2020

Katie Weiner

Genomics

Anti-biofilm efficacy of a medieval treatment for bacterial infection requires the combination of multiple ingredients

Jessica Furner-Pardoe, Blessing O Anonye, Ricky Cain, et al.

AND

The safety profile of Bald’s eyesalve for the treatment of bacterial infections

Blessing O Anonye, Valentine Nweke, Jessica Furner-Pardoe, et al.

Selected by 26 May 2020

Snehal Kadam

Microbiology

The antimicrobial peptide DGL13K is active against resistant gram-negative bacteria and subinhibitory concentrations stimulate bacterial growth without causing resistance

Sven-Ulrik Gorr, Hunter V. Brigman, Jadyn C. Anderson, et al.

Selected by 17 May 2020

Zhang-He Goh

Pharmacology and Toxicology

Retrospective identification of rare cell populations underlying drug resistance connects molecular variability with cell fate

Benjamin L. Emert, Christopher Coté, Eduardo A. Torre, et al.

Selected by 27 April 2020

Pavithran Ravindran

Systems Biology

Automated continuous evolution of proteins in vivo

Ziwei Zhong, Brandon G. Wong, Arjun Ravikumar, et al.

Selected by 27 April 2020

Pavithran Ravindran

Synthetic Biology

Triclosan depletes the membrane potential in Pseudomonas aeruginosa biofilms inhibiting aminoglycoside induced adaptive resistance

Michael M. Maiden, Christopher M. Waters

Selected by 27 April 2020

Amberley Stephens

Microbiology
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